SL Benfica lost on away field in the 1st leg. So they will make a comeback in this home game, to qualify for next round.
In the last time, SL Benfica have won and ended their 4-game winless streak, which boosts their morale.
Moreover, SL Benfica have played well at home, winning 9 of their last 10 home games.
Although FC Shakhtar Donetsk have a stronger record away from home, most of that come from the domestic games.
In addition, the AH line is -0.5 for the home side, which is in favor of SL Benfica.
So the favorites are expected to win.