Tottenham are unbeaten for their last 5 games, including a resounding win over the defending champions Man City last time out in the league.
As for Southampton, they are in a winless run lately, with poor form.
Tottenham have got 1 win, 1 draw and 1 loss in their 3 encounters with Southampton this season in the league and the Cup fixtures.
But now the AH line is -0.75 for the hosts, which is in favor of a home win.
So Tottenham are expected to win this home game and make into the next round.