Valencia have lost the 1st leg with 1-4, so they have to play all-out attacks back to home field. They need at least 3 goals to make a comeback. Besides, Valencia have been unbeaten for 12 successive home matches now.
As for Atalanta, they are also in good form lately, and they have enough stamina reserves. However, their away records in European competitions are not ideal. Besides, they will not play aggressively in this match as they have a huge leading advantage in the 1st leg.
So Valencia are expected to remain unbeaten in this home match.